Human peripheral blood lymphocyte activation by protein A from Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Inhibition of complement activation by a secreted Staphylococcus aureus protein.
Staphylococcus aureus can cause a variety of acute and chronic diseases. The ability of S. aureus to cause persistent infections has been linked to its ability to evade or inactivate host immune responses. We have identified a secreted 19-kDa protein produced by S. aureus that binds to the complement protein C3. N-terminal sequencing of this protein identified it as the extracellular fibrinogen...
متن کاملRapid Detection of Vibrio Cholera by a Coagglutination Complex using Staphylococcus aureus Including Protein A
Introduction: Vibrio cholera is a gram-negative bacterium that causes cholera which is an acute diarrheal illness. Cholera outbreak mostly happens in hot seasons when the bacteria reproduce rapidly in water contaminated with feces. Severe diarrhea and mortality have been the prevalent symptoms of cholera which affect the hygienic status and economic features of humans during centuries. There is...
متن کاملProthrombin activation by a metalloprotease from Staphylococcus aureus.
Formation of thrombin during incubation of purified bovine prothrombin with purified staphylococcal metalloprotease has been investigated. Thrombin activity was estimated by examination of clotting time and by digestion of a synthetic substrate, Chromozym TH. The metalloprotease caused direct activation of prothrombin which was inhibited by the addition of ethylenediaminetetraacetic acid. Metal...
متن کاملFibronectin binding protein A of Staphylococcus aureus can mediate human T lymphocyte adhesion and coactivation.
The extracellular matrix protein fibronectin (FN) mediates the adhesion of bacteria as well as T lymphocytes. Mammalian cells express integrins alpha(4)beta(1) and alpha(5)beta(1) as the major FN-binding cell surface receptors. Bacteria such as Staphylococcus aureus, also express FN-binding receptors that are important for adherence to host tissue and initiation of infection. The S. aureus FN-b...
متن کاملPeripheral Blood Lymphocyte Activation and RANTES Levels in Asthma
Aim: Bronchial mucosal inflammation is one of the major characteristics of atopic asthma. Th2 activation and the related cytokine profile, eosinophil activation and infiltration play the main role in the pathogenesis of atopic asthma. The aim of this study was to demonstrate the activation and RANTES (regulated on activation, normal T-cell expressed and presumably secreted) expression of periph...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1982
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.36.1.59-65.1982